Description

.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(2-Iodophenyl)Methyl-2-o-Methyl- is a sophisticated, high-purity carbohydrate derivative featuring a unique 1,6-anhydro bridge and an ortho-iodophenylmethyl ether moiety. This compound is a critical advanced synthetic intermediate for the development of novel bioactive molecules, offering a rigid sugar scaffold for targeted molecular design. It is primarily utilized by pharmaceutical R&D and academic research laboratories focused on medicinal chemistry, particularly in the synthesis of nucleoside analogs, enzyme inhibitors, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs and antiviral/antitumor drug candidates.
• Medicinal Chemistry Research: Used as a constrained sugar scaffold to study structure-activity relationships (SAR) and improve drug-like properties such as metabolic stability and target affinity.
• Glycochemistry & Glycobiology: Serves as a specialized precursor for constructing complex oligosaccharides or glycomimetics with specific functionalization.
• Chemical Biology Probe Development: The iodine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling the creation of labeled probes for biological studies.
• Academic & Institutional Research: Employed in synthetic organic chemistry projects to develop new methodologies for carbohydrate modification and C-glycoside formation.

Basic Information

Product Name	.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(2-Iodophenyl)Methyl-2-o-Methyl-
CAS No.	112338-85-9
Molecular Formula	C14H17IO4
Molecular Weight	376.19 g/mol
Synonyms	1,6-Anhydro-3-deoxy-4-O-[(2-iodophenyl)methyl]-2-O-methyl-β-D-ribo-hexopyranose; 3-Deoxy-4-O-(2-iodobenzyl)-2-O-methyl-1,6-anhydro-β-D-ribo-hexopyranose; 4-O-(2-Iodobenzyl)-2-O-methyl-1,6-anhydro-3-deoxy-β-D-ribo-hexopyranose; Methyl 2-O-methyl-3-deoxy-4-O-(2-iodobenzyl)-β-D-ribo-hexopyranoside 1,6-anhydride; β-D-ribo-Hexopyranose, 1,6-anhydro-3-deoxy-4-O-[(2-iodophenyl)methyl]-2-O-methyl-
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with exacting standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.