Description

1,5-Dichloro-2-Fluoro-4-Trifluoromethyl-Benzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new fluorination methodologies and the effects of polyhalogenation.

Basic Information

Product Name	1,5-Dichloro-2-Fluoro-4-Trifluoromethyl-Benzene
CAS No.	112290-01-4
Molecular Formula	C7H2Cl2F4
Molecular Weight	248.99 g/mol
Synonyms	2,4-Dichloro-5-fluorobenzotrifluoride; 4-Trifluoromethyl-1,5-dichloro-2-fluorobenzene; 1,5-Dichloro-2-fluoro-4-(trifluoromethyl)benzene; 2,4-Dichloro-α,α,α-trifluoro-5-fluorotoluene; 5-Fluoro-2,4-dichlorobenzotrifluoride; Benzene, 1,5-dichloro-2-fluoro-4-(trifluoromethyl)-; 2,4-Dichloro-5-fluoro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-2-Fluoro-4-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of fine chemical and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.