Description

1-Benzyl-1,4,7,10-Tetraazacyclododecane is a functionalized macrocyclic ligand belonging to the cyclen family, a crucial building block in coordination chemistry. Its primary value lies in its ability to chelate metal ions with high affinity and selectivity, forming stable complexes for advanced applications. This compound is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and materials science sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor for synthesizing novel MRI contrast agents, particularly gadolinium-based complexes.
• Diagnostic Agent Development: Used in the research and production of radiopharmaceuticals for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) imaging.
• Catalysis Research: Acts as a sophisticated ligand for transition metal catalysts in organic synthesis and polymerization processes.
• Chemical Sensing: Employed in the design of fluorescent or colorimetric sensors for metal ion detection in analytical chemistry.
• Bioconjugation: The benzyl group provides a handle for further functionalization, enabling attachment to biomolecules like antibodies or peptides for targeted imaging.
• Materials Science: Used in the development of functional materials, including metal-organic frameworks (MOFs) and luminescent materials.

Basic Information

Product Name	1-Benzyl-1,4,7,10-Tetraazacyclododecane
CAS No.	112193-83-6
Molecular Formula	C₁₇H₃₀N₄
Molecular Weight	290.45 g/mol
Synonyms	1-Benzyl-1,4,7,10-tetraazacyclododecane; Benzylcyclen; 1-Benzyl-1,4,7,10-tetraazacyclododecane; N-Benzyl-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane, 1-benzyl-; Bn-cyclen; Bn-DO3A precursor; 1-Benzyl-1,4,7,10-tetraazacyclododecane (ligand)
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1,4,7,10-Tetraazacyclododecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.