Description

4-Chloro-6-Ethoxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) for the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antimalarial and anticancer drug candidates.
• Organic Synthesis Reagent: Used as a versatile precursor for constructing complex heterocyclic compounds in medicinal chemistry research.
• Agrochemical Research: Intermediate in the development of new fungicides and herbicides due to its bioactive quinoline core.
• Material Science: Potential precursor for the synthesis of organic ligands and functional materials.
• Academic & Industrial R&D: Serves as a standard or starting material for method development and scale-up studies in chemical process optimization.

Basic Information

Product Name	4-Chloro-6-Ethoxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	112190-03-1
Molecular Formula	C₁₅H₁₆ClNO₃
Molecular Weight	293.75 g/mol
Synonyms	Ethyl 4-Chloro-6-ethoxyquinoline-3-carboxylate; 4-Chloro-6-ethoxy-3-quinolinecarboxylic Acid Ethyl Ester; 6-Ethoxy-4-chloroquinoline-3-carboxylic Acid Ethyl Ester; Quinoline-3-carboxylic acid, 4-chloro-6-ethoxy-, ethyl ester; Ethyl 4-chloro-6-ethoxyquinoline-3-carboxylate; 112190-03-1; 4-Chloro-6-ethoxyquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Ethoxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.