Description

(R)-(-)-5-(2-Aminopropyl)-2-Methoxybenzenesulphonamide Hcl CAS NO 112101-77-6 is a high-purity chiral intermediate and active pharmaceutical ingredient (API) of significant commercial importance. Its primary value lies in its role as a key building block for the synthesis of complex, optically active pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. This compound is essential for research institutions, pharmaceutical development laboratories, and manufacturers requiring a reliable source of a specific enantiomer for drug discovery and production.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel therapeutic agents, particularly those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the manufacturing process of specific enantiomerically pure APIs for final drug formulations.
• Neurological & Psychiatric Drug Research: Serves as a precursor in the development of potential treatments for conditions such as depression, anxiety, and attention deficit disorders.
• Asymmetric Synthesis: Employed in advanced organic chemistry to construct molecules with specific three-dimensional configurations.
• Reference Standard: Used in analytical laboratories as a high-purity standard for method development, validation, and quality control testing.
• Process Chemistry & Scale-up: Integral to process optimization and the commercial-scale production of target drug molecules.

Basic Information

Product Name	(R)-(-)-5-(2-Aminopropyl)-2-Methoxybenzenesulphonamide Hydrochloride
CAS No.	112101-77-6
Molecular Formula	C11H18N2O3S • HCl
Molecular Weight	294.80 g/mol
Synonyms	(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide hydrochloride; (R)-(-)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide HCl; (R)-Methoxysulphonamide Hcl; (R)-enantiomer of 5-(2-Aminopropyl)-2-methoxybenzenesulphonamide hydrochloride; (R)-APMBS Hcl; (R)-(-)-APMBS Hydrochloride; (R)-2-Methoxy-5-(2-aminopropyl)benzenesulfonamide hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(-)-5-(2-Aminopropyl)-2-Methoxybenzenesulphonamide Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (R)-enantiomer
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.