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n-Acetyl-9-(Acetylamino)-9-Deoxyneuraminic Acid CAS NO 112054-78-1


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CAS No.:112054-78-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Acetyl-9-(Acetylamino)-9-Deoxyneuraminic Acid is a chemically modified derivative of neuraminic acid, a key component of sialic acids. This compound is a crucial advanced intermediate and research standard for the synthesis and study of more complex sialylated glycoconjugates. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and fine chemical manufacturers engaged in glycobiology, antiviral drug development, and the production of high-value biochemical reagents.

Application

  • Glycobiology Research: Serves as a critical building block and reference standard for studying sialic acid metabolism, cell surface recognition, and signaling pathways.
  • Antiviral Drug Development: Used as an intermediate in the synthesis of neuraminidase inhibitors and other compounds targeting viral adhesion and entry mechanisms.
  • Bioconjugation & Probe Synthesis: Acts as a starting material for creating labeled sialic acid derivatives used in diagnostic assays and imaging studies.
  • Enzymology Studies: Employed as a substrate or inhibitor for sialyltransferases, neuraminidases, and other enzymes involved in glycosylation processes.
  • Fine Chemical Synthesis: A key intermediate for the custom synthesis of complex oligosaccharides and glycopeptides for therapeutic and diagnostic applications.

Basic Information

Product Name n-Acetyl-9-(Acetylamino)-9-Deoxyneuraminic Acid
CAS No. 112054-78-1
Molecular Formula C13H22N2O9
Molecular Weight 350.32 g/mol
Synonyms 9-Acetamido-9-deoxy-N-acetylneuraminic acid; 5-Acetamido-9-acetamido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-ulosonic acid; 9-Acetamido-9-deoxy-Neu5Ac; N-Acetyl-9-acetamido-9-deoxyneuraminic acid; 9-N,5-N-Diacetyl-9-deoxyneuraminic acid; Sialic Acid Derivative; Modified Neuraminic Acid
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Quality Control

Our n-Acetyl-9-(Acetylamino)-9-Deoxyneuraminic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay results, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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