Description

1-(4-Cl-2-Fluorophenyl)-4-Difluoromethyl-4,5-Dihydro-3-Methyl-1H-1,2,4-Triazol-5-(1H)One is a high-purity, advanced heterocyclic compound featuring a unique triazolone core with fluorinated and chlorinated aromatic substituents. This specialized structure makes it a critical building block for the synthesis of novel active ingredients, particularly in the agrochemical and pharmaceutical sectors. It is primarily sought by R&D chemists and process development scientists working on next-generation crop protection agents and bioactive molecules.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern fungicides, herbicides, and insecticides, leveraging its fluorinated triazolone scaffold for enhanced biological activity and environmental profile.
• Pharmaceutical Research: Serves as a versatile scaffold in medicinal chemistry for developing new therapeutic agents, where the difluoromethyl and halogenated phenyl groups can modulate potency, selectivity, and metabolic stability.
• Chemical Synthesis: Used as a specialized reagent for constructing complex nitrogen-containing heterocycles in advanced organic synthesis and process chemistry.
• Material Science Research: Potential application as a monomer or functional additive in the development of high-performance polymers with specific thermal or chemical resistance properties.

Basic Information

Product Name	1-(4-Cl-2-Fluorophenyl)-4-Difluoromethyl-4,5-Dihydro-3-Methyl-1H-1,2,4-Triazol-5-(1H)One
CAS No.	111992-05-3
Molecular Formula	C11H9ClF3N3O
Molecular Weight	291.66 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)-4-(difluoromethyl)-4,5-dihydro-3-methyl-1H-1,2,4-triazol-5-one; 4,5-Dihydro-1-(4-chloro-2-fluorophenyl)-4-(difluoromethyl)-3-methyl-1H-1,2,4-triazol-5-one; 1H-1,2,4-Triazol-5(1H)-one, 1-(4-chloro-2-fluorophenyl)-4,5-dihydro-4-(difluoromethyl)-3-methyl-; CAS 111992-05-3; 1-(4-Chloro-2-fluorophenyl)-4-(difluoromethyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
EINECS	Contact for details

Quality Control

Our production of 1-(4-Cl-2-Fluorophenyl)-4-Difluoromethyl-4,5-Dihydro-3-Methyl-1H-1,2,4-Triazol-5-(1H)One adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistent high quality and reliable performance in your synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be moisture-sensitive; handle and store under inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.