Description

5-(4-Fluorophenyl)-2-Methyl-3-Furoic Acid is a high-value fluorinated heterocyclic building block with significant synthetic utility. This compound is prized for its role as a key intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorophenyl moiety enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors, due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in fluorinated compounds.

Basic Information

Product Name	5-(4-Fluorophenyl)-2-Methyl-3-Furoic Acid
CAS No.	111787-88-3
Molecular Formula	C12H9FO3
Molecular Weight	220.20 g/mol
Synonyms	3-Furoic acid, 5-(4-fluorophenyl)-2-methyl-; 2-Methyl-5-(4-fluorophenyl)-3-furancarboxylic acid; 5-(p-Fluorophenyl)-2-methyl-3-furoic acid; 2-Methyl-5-(4-fluorophenyl)furan-3-carboxylic acid; 111787-88-3; 5-(4-Fluorophenyl)-2-methylfuran-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluorophenyl)-2-Methyl-3-Furoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance in cGMP and ISO 9001 environments for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.