Description

Propargylcholine is a specialized choline derivative featuring a terminal alkyne (propargyl) functional group. This unique molecular structure makes it a valuable chemical building block and research reagent for advanced organic synthesis and biochemical studies. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and academic institutions engaged in medicinal chemistry and probe development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel acetylcholinesterase inhibitors and other bioactive molecules targeting the cholinergic system.
• Click Chemistry Reagent: The alkyne group enables efficient, selective conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe labeling.
• Biochemical Research: Used in studies of choline metabolism, acetylcholine synthesis pathways, and the development of molecular probes for imaging and diagnostic applications.
• Agrochemical Synthesis: Acts as an intermediate in the development of new plant growth regulators or pesticides with novel modes of action.
• Material Science: Potential monomer or cross-linking agent for creating functional polymers with tailored properties.

Basic Information

Product Name	Propargylcholine
CAS No.	111755-76-1
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	2-Hydroxy-N,N,N-trimethyl-3-butyn-1-aminium; 3-Butyn-1-ol, 2-(trimethylammonio)-, hydroxide, inner salt; Propargylcholine hydroxide inner salt; N,N,N-Trimethyl-3-butyn-2-ol-1-aminium; (3-Hydroxy-1-butyn-1-yl)trimethylammonium
EINECS	Contact for details

Quality Control

Our Propargylcholine is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results for assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.