Description

Hyaluronic Acid Ethyl Ester is a chemically modified derivative of hyaluronic acid, where ethyl ester groups enhance its lipophilicity and skin penetration capabilities. This modification is crucial for creating more stable and bioavailable formulations in advanced cosmetic and biomedical products. It is primarily sought by manufacturers in the cosmeceutical, dermal filler, and advanced wound care sectors for its superior film-forming and moisturizing properties.

Application

• Anti-Aging & Moisturizing Serums/Creams: As a key active ingredient for deep hydration and wrinkle reduction.
• Dermal Fillers & Injectable Implants: Used in cross-linked forms for volumizing and contouring applications.
• Advanced Wound Dressings: Promotes a moist healing environment and supports tissue regeneration.
• Professional Skincare & Microneedling Solutions: Enhances product delivery and efficacy in clinical skincare treatments.
• Pharmaceutical Topical Gels: Serves as a bioadhesive carrier for transdermal drug delivery systems.
• Ophthalmic Formulations: Used in eye drops and surgical aids for its viscoelastic and protective properties.

Basic Information

Product Name	Hyaluronic Acid Ethyl Ester
CAS No.	111745-19-8
Molecular Formula	(C14H21NO11)n
Molecular Weight	Variable (Polymer)
Synonyms	HAE
Ethyl Hyaluronate
Hyaluronic Acid Ethyl Ester Sodium Salt
Hyaluronan Ethyl Ester
Ethyl Ester of Hyaluronic Acid
Hyaluronic Acid Ethyl Ester Crosspolymer
INCI: Hyaluronic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Hyaluronic Acid Ethyl Ester is produced under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for purity, molecular weight distribution, and esterification degree. Certificates of Analysis (COA) documenting identity, assay, and microbiological quality are available for all shipments. We support compliance with ISO, GMP, and REACH standards as required for global pharmaceutical and cosmetic supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white fibrous solid or powder
Identification (IR)	Conforms to reference spectrum
Assay (Hyaluronic Acid Content)	≥ 95.0% (on dried basis)
Degree of Esterification	Customizable (e.g., 50% - 90%)
Molecular Weight (Average)	Customizable (e.g., 50 kDa - 500 kDa)
pH (1% Solution)	5.0 - 7.5
Loss on Drying	≤ 10.0 %
Residue on Ignition (Sulfated Ash)	≤ 2.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Microbiological Quality	Total Aerobic Microbial Count ≤ 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.