Description

(8β,9S)-1-Benzyl-1-Azoniacinchonan-9-Ol CAS NO 111300-53-9 is a high-purity, quaternary ammonium derivative of cinchona alkaloid, specifically engineered for advanced chemical synthesis and catalysis. This compound is valued for its role as a sophisticated chiral phase-transfer catalyst and a key intermediate in the production of enantiomerically pure pharmaceuticals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and high-value specialty chemicals.

Application

• Chiral Phase-Transfer Catalysis (PTC): Employed in asymmetric alkylation, Michael addition, and other stereoselective carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the development of chiral ligands and catalysts for producing high-value specialty chemicals.
• Agrochemical Research: Applied in the creation of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization.
• Fine Chemical Production: Facilitates the manufacture of complex molecules with high enantiomeric excess for flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(8β,9S)-1-Benzyl-1-Azoniacinchonan-9-Ol
CAS No.	111300-53-9
Molecular Formula	C₂₇H₃₄N₂O
Molecular Weight	402.57 g/mol
Synonyms	1-Benzylcinchoninium hydroxide; N-Benzylcinchoninium salt; (8β,9S)-1-Benzyl-1-azoniacinchonan-9-ol; Cinchoninium, 1-benzyl-, hydroxide; Cinchona alkaloid PTC catalyst; Benzylcinchoninium; N-Benzylcinchoninium hydroxide; Asymmetric phase transfer catalyst
EINECS	Contact for details

Quality Control

Every batch of (8β,9S)-1-Benzyl-1-Azoniacinchonan-9-Ol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis and impurity profiling, to ensure compliance with research and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.