Description

1,6-Diazabicyclo[3.1.0]Hexane-5-Carboxylicacid,Methylester,[1S-(1Alpha,5Alpha,6Alpha)]- is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused ring structure and defined stereochemistry make it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Agrochemical Synthesis: Used as a building block for creating advanced, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs or molecular probes.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, specialty chemicals requiring specific stereochemical control.

Basic Information

Product Name	1,6-Diazabicyclo[3.1.0]Hexane-5-Carboxylicacid,Methylester,[1S-(1Alpha,5Alpha,6Alpha)]-
CAS No.	111265-50-0
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(1S,5S,6S)-Methyl 1,6-diazabicyclo[3.1.0]hexane-5-carboxylate; (1S,5S,6S)-1,6-Diazabicyclo[3.1.0]hexane-5-carboxylic acid methyl ester; (1S,5S,6S)-5-Methoxycarbonyl-1,6-diazabicyclo[3.1.0]hexane; Methyl (1S,5S,6S)-1,6-diazabicyclo[3.1.0]hexane-5-carboxylate; (1S,5S,6S)-DABCO-5-carboxylic acid methyl ester; (1S,5S,6S)-1,6-Diazabicyclo[3.1.0]hexan-5-yl methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1,6-Diazabicyclo[3.1.0]Hexane-5-Carboxylicacid,Methylester,[1S-(1Alpha,5Alpha,6Alpha)]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.