Description

2,6-Dichloroquinazolin-4-Amine is a versatile halogenated quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering distinct sites for nucleophilic substitution and further functionalization to create complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, dyes, and pigments.
• Academic & R&D: Employed in medicinal chemistry and organic synthesis laboratories for method development and exploring new chemical entities.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs to produce client-specific target molecules.

Basic Information

Product Name	2,6-Dichloroquinazolin-4-Amine
CAS No.	111218-91-8
Molecular Formula	C8H5Cl2N3
Molecular Weight	214.05 g/mol
Synonyms	4-Amino-2,6-dichloroquinazoline; 2,6-Dichloro-4-quinazolinamine; 2,6-Dichloro-4-aminoquinazoline; 4-Quinazolinamine, 2,6-dichloro-; 2,6-Dichloroquinazolin-4-ylamine; 111218-91-8; 2,6-Dichloro-4-quinazolamine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloroquinazolin-4-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.