Description

1-(4-Amino-7-Chloro-6,8-Dinitro-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine HCl is a high-purity, complex heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its intricate molecular structure, featuring a quinazolinyl core with nitro and amino substituents linked to a furanoyl-piperazine moiety, makes it a valuable intermediate for synthesizing novel bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially for targeted therapies.
• Chemical Biology Research: Used as a probe or building block in studying protein-ligand interactions and enzyme inhibition due to its complex structure.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Academic Research: Employed in universities and R&D labs for synthesizing novel heterocyclic compounds and exploring new chemical spaces.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery programs for client pharmaceutical companies.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening against various biological targets.

Basic Information

Item	Details
Product Name	1-(4-Amino-7-Chloro-6,8-Dinitro-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine HCl
CAS No.	111218-75-8
Molecular Formula	C₁₇H₁₄ClN₇O₆ • HCl
Molecular Weight	484.70 g/mol
Synonyms	1-(4-Amino-7-chloro-6,8-dinitro-2-quinazolinyl)-4-(2-furoyl)piperazine hydrochloride; 4-Amino-7-chloro-6,8-dinitro-2-[4-(2-furoyl)-1-piperazinyl]quinazoline hydrochloride; 111218-75-8; Furoylpiperazine quinazoline derivative HCl; 2-[4-(Furan-2-carbonyl)piperazin-1-yl]-4-amino-7-chloro-6,8-dinitroquinazoline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Amino-7-Chloro-6,8-Dinitro-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine HCl is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and mass spectrometry. We are committed to meeting the exacting standards required for research-grade and pharmaceutical intermediate chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and desiccated to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.