Description

1-(4-Amino-6-Bromo-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its quinazolinyl and piperazine motifs.
• Biochemical Research: Serves as a reference standard or a precursor for probe molecules in biochemical and pharmacological assays.
• Custom Synthesis: Employed by fine chemical suppliers for the custom manufacturing of specialized compounds for client R&D projects.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	1-(4-Amino-6-Bromo-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine Hydrochloride
CAS No.	111218-73-6
Molecular Formula	C₁₇H₁₅BrN₆O₂·HCl
Molecular Weight	459.71 g/mol (Free base: 423.25 g/mol)
Synonyms	4-Amino-6-bromo-2-[4-(2-furoyl)piperazin-1-yl]quinazoline hydrochloride; 1-(4-Amino-6-bromoquinazolin-2-yl)-4-(furan-2-carbonyl)piperazine hydrochloride; 111218-73-6; 4-Amino-6-bromo-2-(4-(2-furoyl)-1-piperazinyl)quinazoline HCl; 2-[4-(2-Furoyl)-1-piperazinyl]-6-bromo-4-quinazolinamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-6-Bromo-2-Quinazolinyl)-4-(2-Furanylcarbonyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation upon exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.