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α-Neunac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-[α-Fuc-(1->3)]-Glc CAS NO 111216-36-5
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CAS No.:111216-36-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
α-Neunac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-[α-Fuc-(1->3)]-Glc CAS NO 111216-36-5 is a complex, high-purity oligosaccharide, specifically a sialylated and fucosylated glycan structure. This compound is critical for advanced research in glycobiology, serving as a key reference standard and synthetic intermediate. It is primarily needed by pharmaceutical R&D teams, diagnostic developers, and academic institutions focused on carbohydrate chemistry, biomarker discovery, and the development of glycan-based therapeutics.
Application
- Glycobiology Research: Used as a high-purity reference standard for analyzing glycan structures and biosynthetic pathways.
- Pharmaceutical Development: Serves as a crucial intermediate or building block for synthesizing complex carbohydrate-based drugs, including selectin inhibitors and anti-inflammatory agents.
- Diagnostic Reagent Synthesis: Employed in the development of diagnostic assays and kits that detect specific glycan biomarkers associated with diseases like cancer.
- Enzyme Substrate Studies: Acts as a specific substrate for studying the activity and kinetics of glycosyltransferases, sialidases, and fucosidases.
- Cell Signaling & Immunology Research: Utilized to investigate the role of sialylated and fucosylated glycans in cell-cell recognition, immune response modulation, and pathogen-host interactions.
- Bioconjugation & Probe Development: Functionalized for creating glycan arrays, fluorescent probes, or bioconjugates for high-throughput screening and imaging studies.
Basic Information
| Product Name | α-Neunac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-[α-Fuc-(1->3)]-Glc |
| CAS No. | 111216-36-5 |
| Molecular Formula | C46H76N2O36 |
| Molecular Weight | 1185.09 g/mol |
| Synonyms | 6'-Sialyl-N-acetyllactosamine; Sialyl Lewis X precursor; Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4(Fucα1-3)Glc; Sialylated Lacto-N-neotetraose; LST c derivative; 6'-SLN; Sialyl Lex Core Structure; Glycan 111216-36-5 |
| EINECS | Contact for details |
Quality Control
Every batch of this oligosaccharide is produced and analyzed under strict quality protocols to ensure high purity and structural integrity, suitable for sensitive research applications. Our quality commitment includes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
| Bacterial Endotoxins | < 10 EU/mg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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