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3-Deoxy-8-o-(3-o-Rhamnopyranosyl-Rhamnopyranosyl)-Manno-Octulosonate CAS NO 111070-81-6
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CAS No.:111070-81-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Deoxy-8-o-(3-o-Rhamnopyranosyl-Rhamnopyranosyl)-Manno-Octulosonate is a complex, high-purity carbohydrate derivative, specifically a disaccharide of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo). This compound serves as a critical intermediate and reference standard in advanced biochemical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on glycobiology, bacterial polysaccharide synthesis, and vaccine development. Its defined structure is essential for studying molecular interactions and developing novel therapeutic agents.
Application
- Glycobiology Research: A key intermediate for studying the biosynthesis and function of complex bacterial lipopolysaccharides (LPS) and cell wall components.
- Pharmaceutical R&D: Used as a reference standard and building block in the development of novel antibiotics, anti-infectives, and conjugate vaccines targeting Gram-negative bacteria.
- Enzymology Studies: Serves as a specific substrate for enzymes like Kdo transferases, enabling kinetic studies and inhibitor screening.
- Analytical Standard: Employed in HPLC, MS, and NMR for method development, calibration, and qualitative/quantitative analysis of related carbohydrate structures.
- Synthetic Chemistry: Acts as a sophisticated starting material for the chemical and enzymatic synthesis of more complex oligosaccharides and glycoconjugates.
Basic Information
| Product Name | 3-Deoxy-8-o-(3-o-Rhamnopyranosyl-Rhamnopyranosyl)-Manno-Octulosonate |
| CAS No. | 111070-81-6 |
| Molecular Formula | C20H32O16 |
| Molecular Weight | 528.46 g/mol |
| Synonyms | Kdo-α-(2→4)-Kdo; 3-Deoxy-D-manno-oct-2-ulosonic acid-(2→4)-3-deoxy-D-manno-oct-2-ulosonic acid; Kdo disaccharide; α-Kdo-(2→4)-α-Kdo; 8-O-[3-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-rhamnopyranosyl]-3-deoxy-D-manno-oct-2-ulopyranosonic acid; Bacterial LPS core disaccharide; Kdo2; Lipid A precursor disaccharide |
| EINECS | Contact for details |
Quality Control
Our 3-Deoxy-8-o-(3-o-Rhamnopyranosyl-Rhamnopyranosyl)-Manno-Octulosonate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and MS, to ensure structural identity and high purity suitable for research applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency for your critical projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (NMR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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