Description

L-Serine, n-(Triphenylmethyl)-, Compd. With N,n-Diethylethanamine (1:1) is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise control over peptide and protein structure during complex multi-step reactions. It is primarily utilized in the pharmaceutical industry for the development of novel therapeutic peptides, as well as in academic and industrial research laboratories for biochemical studies.

Application

• Pharmaceutical Intermediate: A key protected synthon in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics for drug discovery and development.
• Biochemical Research: Used in the study of enzyme mechanisms, protein folding, and as a precursor for labeled compounds in metabolic pathway analysis.
• Protecting Group Strategy: The triphenylmethyl (trityl) group provides orthogonal protection for the serine side chain, enabling selective deprotection in multi-functional molecule synthesis.
• Ligand and Catalyst Development: Serves as a chiral precursor for the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	L-Serine, n-(Triphenylmethyl)-, Compd. With N,n-Diethylethanamine (1:1)
CAS No.	111061-44-0
Molecular Formula	C28H34N2O3
Molecular Weight	446.58 g/mol
Synonyms	N-Trityl-L-serine triethylamine salt; L-Serine, N-(triphenylmethyl)-, compd. with N,N-diethylethanamine (1:1); Fmoc-Ser(Trt)-OH·TEA; Nα-Trityl-L-serine triethylammonium salt; O-Trityl-L-serine TEA salt; Ser(Trt)-OH x TEA; Protected L-serine triethylamine complex; Trityl-L-serine triethylamine adduct
EINECS	Contact for details

Quality Control

Our L-Serine, n-(Triphenylmethyl)-, Compd. With N,n-Diethylethanamine (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR, to ensure it meets the stringent requirements for pharmaceutical research and synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.