Description

Ethyl (2S)-2,3-Epoxypropanoate is a high-value chiral epoxide ester, a key building block in asymmetric synthesis. This optically active compound is essential for introducing the (2S)-glycidyl moiety into target molecules with high stereochemical fidelity. It is primarily utilized by pharmaceutical, agrochemical, and fine chemical research and development teams for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and chiral ligands.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the production of β-blockers, antiviral agents, and other enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the manufacture of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Asymmetric Catalysis Research: Employed as a substrate or building block in the development of new chiral catalysts and methodologies.
• Polymer Modification: Can be used to introduce reactive epoxy and ester functionalities into polymer chains.

Basic Information

Product Name	Ethyl (2S)-2,3-Epoxypropanoate
CAS No.	111058-34-5
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(S)-Ethyl Glycidate; (S)-Ethyl Oxiranecarboxylate; (-)-Ethyl Glycidate; (2S)-Oxiranecarboxylic Acid Ethyl Ester; L-Ethyl Glycidate; Ethyl (S)-Glycidate; (S)-Glycidic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl (2S)-2,3-Epoxypropanoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.