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1-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)Propan-2-One CAS NO 111011-80-4


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CAS No.:111011-80-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)Propan-2-One is a specialized organophosphorus compound, specifically a cyclic phosphinate ester, valued for its role as a key intermediate in advanced synthesis. Its structure makes it a versatile building block for introducing phosphorus-containing functional groups into target molecules. This chemical is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and functional additives.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring phosphorus-based bioactive moieties.
  • Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides, insecticides, and plant growth regulators.
  • Ligand and Catalyst Development: Employed in the creation of specialized phosphinate ligands for asymmetric catalysis and metal complexation.
  • Flame Retardant Synthon: Acts as a reactive intermediate in the production of phosphorus-containing flame retardants for polymers and textiles.
  • Material Science Research: Utilized in developing functional monomers for specialty polymers, coatings, and adhesives.
  • Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms and biological pathways involving phosphorylation.

Basic Information

Item Details
Product Name 1-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)Propan-2-One
CAS No. 111011-80-4
Molecular Formula C8H15O4P
Molecular Weight 206.18 g/mol
Synonyms 2-Propanone, 1-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-; 5,5-Dimethyl-2-(2-oxopropyl)-2-oxido-1,3,2-dioxaphosphinane; 1-(5,5-Dimethyl-2-oxo-2-oxido-1,3,2-dioxaphosphinan-2-yl)propan-2-one; Acetone cyclic dimethylpropylene phosphite adduct oxide; Cyclic phosphinate ester of acetone
EINECS Contact for details

Quality Control

Every batch of 1-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)Propan-2-One is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Melting Point Contact for details
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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