Description

cis-2-Benzoyl-3-(Trifluoromethyl)Oxirane is a specialized fluorinated oxirane derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity of the oxirane ring combined with the electron-withdrawing trifluoromethyl and benzoyl groups, enabling precise construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated motifs and chiral centers into target molecules, thereby modulating their biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or chiral epoxide precursors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance compound stability and bioavailability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored surface properties or refractive indices.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for ring-opening reactions, nucleophilic additions, and as a scaffold for creating diverse heterocyclic compounds.
• Ligand and Catalyst Development: Useful precursor for synthesizing chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	cis-2-Benzoyl-3-(Trifluoromethyl)Oxirane
CAS No.	110960-53-7
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	2-Benzoyl-3-(trifluoromethyl)oxirane (cis-); (2R,3S)-2-Benzoyl-3-(trifluoromethyl)oxirane; (2S,3R)-2-Benzoyl-3-(trifluoromethyl)oxirane; cis-2-Benzoyl-3-trifluoromethyloxirane; α-Benzoyl-β-(trifluoromethyl)ethylene oxide; 3-Trifluoromethyl-2-benzoyloxirane; Oxirane, 2-benzoyl-3-(trifluoromethyl)-, cis-; Phenyl[3-(trifluoromethyl)oxiran-2-yl]methanone
EINECS	Contact for details

Quality Control

Our cis-2-Benzoyl-3-(Trifluoromethyl)Oxirane is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, NMR, and IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.