Description

5,7-Difluoro-3,4-Dihydro-2H-Naphthalen-1-One is a high-purity fluorinated organic building block, specifically a difluorinated tetralone derivative. This compound is valued for its role as a critical synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought by research and development chemists and process engineers in the fine chemical and pharmaceutical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing a fluorinated naphthalene or tetralin core structure.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the difluoro substitution pattern can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, or organic electronic materials with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for methodological studies, such as asymmetric hydrogenation or cross-coupling reactions, due to its functional handle.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the effects of specific fluorine substitution patterns on chemical reactivity and physical properties.

Basic Information

Product Name	5,7-Difluoro-3,4-Dihydro-2H-Naphthalen-1-One
CAS No.	110931-79-8
Molecular Formula	C₁₀H₈F₂O
Molecular Weight	182.17 g/mol
Synonyms	5,7-Difluoro-1-tetralone; 5,7-Difluoro-3,4-dihydro-2H-naphthalen-1-one; 5,7-Difluoro-1-oxo-1,2,3,4-tetrahydronaphthalene; 1-Tetralone, 5,7-difluoro-; 5,7-Difluoro-α-tetralone; 5,7-Difluoro-3,4-dihydronaphthalen-1(2H)-one
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-3,4-Dihydro-2H-Naphthalen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.