Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-5-[(Ethoxycarbonyl)Amino]-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester is a high-value, structurally complex fluoroquinolone derivative. This compound serves as a critical advanced pharmaceutical intermediate for the synthesis of next-generation antibacterial agents. It is essential for R&D and manufacturing within the global pharmaceutical industry, particularly for companies developing novel antibiotics targeting resistant bacterial strains.

Application

• Key Intermediate for Antibiotic Synthesis: Primary use in the production of advanced fluoroquinolone-class antibacterial drugs.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the design and synthesis of new antimicrobial candidates.
• Active Pharmaceutical Ingredient (API) Manufacturing: A crucial building block in the multi-step synthesis of final API substances.
• Process Chemistry & Scale-Up: Serves as a reference standard and starting material for process optimization and pilot-scale production.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs engaged in the production of specialized antibiotic formulations.
• Academic & Institutional Research: Utilized in biochemical and microbiological studies to understand structure-activity relationships.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-5-[(Ethoxycarbonyl)Amino]-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester
CAS No.	110872-01-0
Molecular Formula	C23H28F2N4O5
Molecular Weight	478.49 g/mol
Synonyms	Ethyl 1-Cyclopropyl-5-[(ethoxycarbonyl)amino]-6,8-difluoro-7-(3-methyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 1-Cyclopropyl-5-[(ethoxycarbonyl)amino]-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxo-5-[(ethoxycarbonyl)amino]quinoline-3-carboxylic Acid Ethyl Ester; Gatifloxacin Ethyl Ester; Gatifloxacin Intermediate; AM-1155 Intermediate; GTX Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.