Description

n-Retinoylleucine is a specialized retinoid derivative of the amino acid leucine, offering a unique molecular structure for advanced research and development. This compound is valued for its potential role in modulating cellular signaling pathways related to differentiation and proliferation. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced cosmetic industries for investigating novel therapeutic and bioactive agents.

Application

• Pharmaceutical Research: Serves as a key intermediate or reference standard in the development of novel retinoid-based therapeutics targeting skin conditions, oncology, and metabolic disorders.
• Biochemical Studies: Used as a molecular probe to study retinoid receptor (RAR/RXR) interactions, signal transduction, and gene expression mechanisms.
• Cosmetic Science: Investigated for potential applications in advanced anti-aging and skin-rejuvenation formulations due to its retinoid activity.
• Nutraceutical Development: Explored as a precursor or active ingredient in the design of specialized dietary supplements targeting cellular health.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex retinoid analogs and peptide conjugates.
• Academic Research: Employed in university and institutional labs for fundamental studies on vitamin A metabolism and its biological effects.

Basic Information

Product Name	n-Retinoylleucine
CAS No.	110769-97-6
Molecular Formula	C26H39NO3
Molecular Weight	413.60 g/mol
Synonyms	Retinoyl-L-leucine; N-[(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl]-L-leucine; L-Leucine, N-[(all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl]-; Retinoic acid leucine amide; Leucine retinamide
EINECS	Contact for details

Quality Control

Our n-Retinoylleucine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.