Description

1-Ethyl-6-Fluoro-3-Formyl-1,4-Dihydro-4-Oxo-7-Piperazinylquinoline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs). It is primarily required by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Antibacterial Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new antibacterial agents.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex nitrogen-containing heterocycles in organic synthesis.
• API Development: Employed in the research and scale-up processes for new Active Pharmaceutical Ingredients targeting bacterial infections.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and chemical research.

Basic Information

Product Name	1-Ethyl-6-Fluoro-3-Formyl-1,4-Dihydro-4-Oxo-7-Piperazinylquinoline
CAS No.	110719-56-7
Molecular Formula	C₁₇H₁₈FN₃O₂
Molecular Weight	315.34 g/mol
Synonyms	7-Piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxaldehyde; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxaldehyde; 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carbaldehyde; 7-(Piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbaldehyde; 110719-56-7; Fluoroquinolone Intermediate; Quinoline-3-carboxaldehyde derivative
EINECS	Contact for details

Quality Control

Our 1-Ethyl-6-Fluoro-3-Formyl-1,4-Dihydro-4-Oxo-7-Piperazinylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.