Description

o-((Nalpha)-Acetylglucosamine 6-Sulfate)-(1-3)-Idonic Acid is a specialized, high-purity sulfated carbohydrate derivative of significant interest in advanced biochemical research and development. This compound serves as a critical building block and reference standard for studying complex glycosaminoglycan (GAG) structures and their biological interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biomaterials. The precise sulfation pattern makes it a valuable tool for investigating carbohydrate-protein interactions relevant to inflammation, cell signaling, and tissue engineering.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the analysis and characterization of complex carbohydrate structures, particularly chondroitin and dermatan sulfate derivatives.
• Enzyme Substrate & Inhibitor Studies: Acts as a specific substrate or inhibitor for sulfatases, glycosidases, and other enzymes involved in GAG metabolism for mechanistic and kinetic studies.
• Pharmaceutical R&D: Serves as a key intermediate or analytical standard in the research and development of carbohydrate-based drugs targeting inflammatory diseases, coagulation disorders, and viral infections.
• Glycomics & Proteomics: Essential tool in glycomics research for elucidating the structure-function relationships of sulfated glycans and their interactions with lectins, growth factors, and chemokines.
• Diagnostic Reagent Development: Employed in the development of diagnostic assays and kits that detect or quantify specific carbohydrate epitopes or enzyme activities.
• Biomaterial Synthesis: Used as a precursor or modifying agent in the synthesis of biofunctionalized hydrogels and scaffolds for tissue engineering and regenerative medicine applications.

Basic Information

Product Name	o-((Nalpha)-Acetylglucosamine 6-Sulfate)-(1-3)-Idonic Acid
CAS No.	110685-78-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Acetylglucosamine 6-sulfate-idonic acid derivative; (1-3)-Linked NAcGlc6S-IdoA; Chondroitin sulfate disaccharide derivative; D-Glucopyranose, 2-(acetylamino)-2-deoxy-6-O-sulfo-, (1-3)-linked to L-idonic acid; 6-Sulfo-N-acetylglucosamine-iduronate; Glycosaminoglycan disaccharide analog; Sulfated N-acetyl-D-glucosaminyl-L-idonate
EINECS	Contact for details

Quality Control

Our o-((Nalpha)-Acetylglucosamine 6-Sulfate)-(1-3)-Idonic Acid is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile. We adhere to relevant guidelines for analytical reference materials to support your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. This compound is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.