Description

2-Chloro-6-Fluoro-4-(Trifluoromethyl)-Phenylhydrazine is a specialized halogenated phenylhydrazine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of high-value, complex molecules, particularly in the agrochemical and pharmaceutical sectors. Industries requiring the synthesis of novel active ingredients, such as crop protection agents and pharmaceutical candidates, will find this intermediate essential for introducing specific halogenated and trifluoromethylated motifs into their target structures.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogen and trifluoromethyl groups.
• Pharmaceutical Synthesis: Serves as a key building block for creating active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and specialty polymers, where specific fluorine substitution patterns are required.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, halogenated dyes and pigments with enhanced stability and color properties.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to introduce the phenylhydrazine moiety into complex molecular architectures.

Basic Information

Product Name	2-Chloro-6-Fluoro-4-(Trifluoromethyl)-Phenylhydrazine
CAS No.	110499-66-6
Molecular Formula	C7H5ClF4N2
Molecular Weight	228.57 g/mol
Synonyms	2-Chloro-6-fluoro-4-(trifluoromethyl)phenylhydrazine; (2-Chloro-6-fluoro-4-(trifluoromethyl)phenyl)hydrazine; 1-(2-Chloro-6-fluoro-4-(trifluoromethyl)phenyl)hydrazine; 2-Chloro-6-fluoro-alpha,alpha,α-trifluoro-p-tolylhydrazine; Hydrazine, [2-chloro-6-fluoro-4-(trifluoromethyl)phenyl]-; 110499-66-6; Phenylhydrazine, 2-chloro-6-fluoro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-4-(Trifluoromethyl)-Phenylhydrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.