Description

(2R)-2-Amino-2-Naphthylethan-1-Ol Hcl CAS NO 110480-83-6 is a high-purity chiral amino alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined naphthyl-ethanolamine scaffold essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), chiral catalysts, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Fine Chemical Production: Used in the synthesis of complex, high-value specialty chemicals requiring the (R)-configured 1-(2-naphthyl)ethanolamine structure.
• Biochemical Research: Utilized in studies of receptor-ligand interactions and enzyme inhibition where the naphthalene moiety is significant.
• Material Science: Potential precursor for chiral dopants or monomers in advanced polymeric materials.

Basic Information

Product Name	(2R)-2-Amino-2-Naphthylethan-1-Ol Hydrochloride
CAS No.	110480-83-6
Molecular Formula	C₁₂H₁₄ClNO
Molecular Weight	223.70 g/mol
Synonyms	(R)-2-Amino-2-(2-naphthyl)ethanol hydrochloride; (2R)-2-Amino-2-(naphthalen-2-yl)ethan-1-ol hydrochloride; (R)-2-Naphthylglycinol hydrochloride; 1-(2-Naphthyl)-2-aminoethanol (R)-hydrochloride; (R)-2-Amino-1-(2-naphthyl)ethanol hydrochloride; AR-2-NG HCl; (R)-2-(2-Aminoethyl)naphthalene hydrochloride
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-Naphthylethan-1-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.