Description

9-Amino-9-Bicyclo[3.3.1]Nonanecarboxylic Acid is a specialized, high-purity bicyclic amino acid derivative with the CAS number 110368-45-1. This compound is valued for its rigid, three-dimensional scaffold, making it a critical building block in advanced pharmaceutical research and peptide mimetic design. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating novel active compounds with enhanced stability and specificity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and receptor antagonist development.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, improving metabolic stability and binding affinity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and protein-protein interactions.
• Agrochemical Research: Employed in the design of new herbicides and pesticides with unique modes of action.
• Material Science: Potential monomer for synthesizing specialty polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Essential for fundamental research in organic synthesis and medicinal chemistry at universities and CROs.

Basic Information

Product Name	9-Amino-9-Bicyclo[3.3.1]Nonanecarboxylic Acid
CAS No.	110368-45-1
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	9-Amino-9-bicyclo[3.3.1]nonane-9-carboxylic acid; 9-Amino-BCNA; 9-Amino-9-carboxybicyclo[3.3.1]nonane; Bicyclo[3.3.1]nonane-9-carboxylic acid, 9-amino-; 9-Aza-9-carboxybicyclo[3.3.1]nonane (tautomeric form); 9-ABNCA; 9-Amino-9-BCN-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 9-Amino-9-Bicyclo[3.3.1]Nonanecarboxylic Acid is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (where applicable), and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.