Description

(S)-2-(4-Fluorophenyl) 3-Methylbutyric Acid is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its defined stereochemistry and functional groups make it a valuable building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced chiral pesticides and herbicides, where specific stereochemistry can influence biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring precise structural control.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling in related API manufacturing.

Basic Information

Product Name	(S)-2-(4-Fluorophenyl) 3-Methylbutyric Acid
CAS No.	110311-45-0
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	(S)-2-(4-Fluorophenyl)-3-methylbutanoic acid; (S)-α-Isopropyl-4-fluorophenylacetic acid; (S)-2-(p-Fluorophenyl)-3-methylbutyric acid; (S)-4-Fluoro-α-(1-methylethyl)benzenacetic acid; (S)-2-(4-Fluorophenyl)-3-methylbutanoate; (S)-Fenoprofen related compound; (S)-Enantiomer of 2-(4-Fluorophenyl)-3-methylbutyric acid
EINECS	Contact for details

Quality Control

Our (S)-2-(4-Fluorophenyl) 3-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.