Description

2S,3S-2-Methyl-Piperidine-3-Carboxylic Acid is a high-purity, non-natural chiral pipecolic acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas like enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective reactions to construct complex molecules with defined three-dimensional structures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Agrochemical Synthesis: Acts as a building block for creating novel chiral pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in metal-catalyzed asymmetric transformations.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.

Basic Information

Product Name	2S,3S-2-Methyl-Piperidine-3-Carboxylic Acid
CAS No.	110287-65-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(2S,3S)-2-Methylpiperidine-3-carboxylic acid; (2S,3S)-2-Methyl-3-piperidinecarboxylic acid; (2S,3S)-2-Methylnipecotic acid; L-threo-2-Methylpipecolic acid; (2S,3S)-2-Methylpipecolic acid; 2-Methyl-DL-pipecolic acid (stereoisomer); 2-Methylpiperidine-3-carboxylic acid (2S,3S-form)
EINECS	Contact for details

Quality Control

Our 2S,3S-2-Methyl-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (2S,3S)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.