Description

Tirilazadmesylate CAS NO 110101-66-1 is a synthetic 21-aminosteroid compound, specifically a potent inhibitor of lipid peroxidation. It is a critical pharmaceutical intermediate and research chemical valued for its neuroprotective properties. This compound is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers focused on developing treatments for central nervous system disorders and ischemia-reperfusion injury.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of neuroprotective drug candidates.
• Research & Development: Used in preclinical and clinical research studies investigating treatments for stroke, traumatic brain injury, and subarachnoid hemorrhage.
• Biochemical Research: Serves as a reference standard and active agent in studies of lipid peroxidation mechanisms and antioxidant pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for novel 21-aminosteroid derivatives.
• Academic Research: Utilized in university and institutional labs for neurological disease modeling and pharmacological studies.

Basic Information

Product Name	Tirilazad Mesylate
CAS No.	110101-66-1
Molecular Formula	C33H48N2O6S
Molecular Weight	600.81 g/mol
Synonyms	Tirilazad Mesylate; U-74006F; 21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16α-methylpregna-1,4,9(11)-triene-3,20-dione monomethanesulfonate; 21-[4-(2,6-Di(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]-16α-methylpregna-1,4,9(11)-triene-3,20-dione methanesulfonate; Tirilazad; U74006F; U 74006F
EINECS	Contact for details

Quality Control

Our Tirilazad Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, residual solvent analysis, and identity confirmation to ensure it meets exacting standards for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.