Description

4,8-Anhydro-n-Acetylneuraminic Acid is a specialized derivative of sialic acid, a key carbohydrate molecule in biological systems. This compound serves as a valuable intermediate and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying carbohydrate metabolism, enzyme mechanisms, and for the synthesis of more complex glycoconjugates.

Application

• Biochemical Research: Used as a critical intermediate and reference standard in studies of sialic acid metabolism, glycosidase enzymes, and carbohydrate-protein interactions.
• Pharmaceutical Development: Serves as a key building block in the synthesis of novel glycoconjugate-based therapeutics, including potential antiviral and anti-inflammatory agents.
• Enzymology Studies: Acts as a substrate or inhibitor for sialidases (neuraminidases) and other glycosyl hydrolases to investigate enzyme kinetics and mechanisms.
• Glycobiology: Employed in the preparation of structurally defined oligosaccharides and glycoconjugates for functional and structural analysis.
• Diagnostic Reagent Manufacturing: Used in the production of high-purity reagents for diagnostic assays targeting sialic acid-related biomarkers.
• Academic Research: A vital tool for universities and research institutions exploring cell surface biology, signaling, and microbial pathogenesis.

Basic Information

Product Name	4,8-Anhydro-n-Acetylneuraminic Acid
CAS No.	109915-63-1
Molecular Formula	C11H17NO9
Molecular Weight	307.25 g/mol
Synonyms	4,8-Anhydro-N-acetylneuraminic acid; 4,8-Anhydro-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid; 4,8-Anhydro-Neu5Ac; Anhydro-N-acetylneuraminic acid; 4,8-Cyclic N-acetylneuraminic acid; 4,8-Lactone of N-acetylneuraminic acid; 4,8-Anhydro-sialic acid
EINECS	Contact for details

Quality Control

Our 4,8-Anhydro-n-Acetylneuraminic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.