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Methyl 2-Acetamido-2-Deoxy-3-o-(α-Idopyranosyluronic Acid)-4-o-Sulfo-β-Galactopyranoside CAS NO 109914-81-0


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CAS No.:109914-81-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-Acetamido-2-Deoxy-3-o-(α-Idopyranosyluronic Acid)-4-o-Sulfo-β-Galactopyranoside is a highly specialized, sulfated carbohydrate derivative that serves as a critical reference standard and building block in advanced biochemical research. This compound is essential for scientists investigating the structure, biosynthesis, and biological functions of complex glycosaminoglycans (GAGs) and proteoglycans. Its primary value lies in enabling precise studies of carbohydrate-protein interactions, enzyme specificity, and metabolic pathways relevant to connective tissue biology and disease mechanisms. Researchers in pharmaceutical development, glycobiology, and diagnostic assay design rely on this high-purity material for its defined structure and consistent performance.

Application

  • Glycobiology Research: Used as a precise substrate or inhibitor in enzymatic assays to study sulfotransferases, glycosidases, and other enzymes involved in GAG metabolism.
  • Pharmaceutical Reference Standard: Serves as an analytical standard for the quality control and characterization of heparin-like compounds, biosimilars, and novel glycan-based therapeutics.
  • Proteoglycan & GAG Synthesis Studies: Acts as a key intermediate or building block in the chemical or chemoenzymatic synthesis of defined oligosaccharide sequences for structure-activity relationship (SAR) studies.
  • Diagnostic Development: Employed in the development of diagnostic tools and assays targeting specific sulfated glycan epitopes associated with diseases like cancer, inflammation, and genetic disorders.
  • Biomaterial Science: Investigated for its potential use in creating bioactive surfaces, hydrogels, or drug delivery systems that mimic the extracellular matrix.
  • Academic & Institutional Research: Fundamental tool for universities and research institutes exploring carbohydrate-mediated cell signaling, pathogen recognition, and developmental biology.

Basic Information

Product Name Methyl 2-Acetamido-2-Deoxy-3-o-(α-Idopyranosyluronic Acid)-4-o-Sulfo-β-Galactopyranoside
CAS No. 109914-81-0
Molecular Formula C15H23NO14S
Molecular Weight 473.41 g/mol
Synonyms Methyl 2-acetamido-2-deoxy-3-O-(α-L-idopyranosyluronic acid)-4-O-sulfo-β-D-galactopyranoside; 4-O-Sulfo-β-D-Galactopyranoside derivative; Iduronic acid-containing disaccharide sulfate; Sulfated N-acetyl-D-galactosamine-iduronic acid methyl glycoside; Heparin disaccharide analog; GAG oligosaccharide model compound; Glycosaminoglycan fragment; CAS 109914-81-0
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Quality Control

Every batch of Methyl 2-Acetamido-2-Deoxy-3-o-(α-Idopyranosyluronic Acid)-4-o-Sulfo-β-Galactopyranoside is produced and analyzed under stringent quality protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant in the storage environment.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms to structure
Purity (HPLC) ≥ 95%
Assay ≥ 90% (by weight)
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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