Description

Ms-Peg8-Ms is a high-purity, bifunctional polyethylene glycol (PEG) derivative, also known as Methoxy-PEG8-Methanesulfonate. This compound serves as a versatile and critical heterobifunctional crosslinker and spacer in advanced chemical synthesis. Its primary value lies in enabling the precise conjugation of molecules, facilitating the development of sophisticated materials and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotech, and advanced materials sectors who require reliable, high-quality building blocks for drug delivery systems, hydrogel formation, and surface functionalization.

Application

• Bioconjugation and Drug Delivery: A key reagent for PEGylating peptides, proteins, and small molecule drugs to enhance solubility, stability, and circulation time.
• Polymer Chemistry: Acts as a chain extender or crosslinking agent in the synthesis of tailored PEG-based hydrogels and block copolymers.
• Surface Modification: Used to functionalize nanoparticles, quantum dots, and other material surfaces with PEG chains to improve biocompatibility and reduce non-specific binding.
• Proteomics Research: Employed as a tool for chemical crosslinking in mass spectrometry studies to analyze protein structures and interactions.
• Diagnostic Reagents: Facilitates the creation of stable conjugates for immunoassays and biosensor development.
• Material Science: Serves as a building block for creating non-fouling coatings and smart, responsive materials.

Basic Information

Product Name	Ms-Peg8-Ms
CAS No.	109789-41-5
Molecular Formula	C19H40O11S2
Molecular Weight	508.64 g/mol
Synonyms	Methoxy-PEG8-methanesulfonate; α-Methoxy-ω-methanesulfonyl-poly(ethylene glycol) (n=8); Poly(ethylene glycol) methyl ether methanesulfonate (MW ~500); mPEG8-OMs; 2,5,8,11,14,17,20,23-Octaoxapentacosane-1,25-diyl dimethanesulfonate (substituted); PEG8 dimethanesulfonate derivative; Heterobifunctional PEG crosslinker; Bis-Ms-mPEG8
EINECS	Contact for details

Quality Control

Every batch of Ms-Peg8-Ms CAS NO 109789-41-5 is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.