Description

1-[4-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-1-Piperazinyl]-5-Hydroxy-1-Pentanone is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Biochemical Research: Serves as a precursor or reference standard in biochemical and pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct sophisticated heterocyclic compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-[4-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-1-Piperazinyl]-5-Hydroxy-1-Pentanone
CAS No.	109678-71-9
Molecular Formula	C19H27N5O4
Molecular Weight	389.45 g/mol
Synonyms	5-Hydroxy-1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-1-pentanone; 1-Pentanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-; 109678-71-9; 4-Amino-6,7-dimethoxy-2-[4-(5-hydroxy-1-oxopentyl)-1-piperazinyl]quinazoline; Quinazoline derivative intermediate
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-1-Piperazinyl]-5-Hydroxy-1-Pentanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.