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(R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) CAS NO 109304-40-7


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CAS No.:109304-40-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) is a sophisticated, multifunctional carbohydrate derivative that serves as a critical building block in advanced pharmaceutical and biochemical research. This compound's unique structure, featuring a phosphorylated sugar core esterified with a hydroxylated fatty acid chain, makes it invaluable for synthesizing complex glycoconjugates and lipid-linked intermediates. It is primarily sought after by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and biochemical probes.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of complex glycopeptide antibiotics and other bioactive molecules targeting bacterial cell walls.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphatases, and glycosyltransferases.
  • Glycoconjugate Synthesis: Essential building block for creating novel vaccine adjuvants, drug delivery carriers, and diagnostic agents based on lipid A or related structures.
  • Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in the search for new anti-infective and immunomodulatory agents.
  • Process Development: Used in scaling up GMP-compliant manufacturing processes for advanced therapeutic candidates.

Basic Information

Product Name (R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate)
CAS No. 109304-40-7
Molecular Formula C22H42NO11P
Molecular Weight 527.54 g/mol
Synonyms 1-O-Phosphono-3-O-(3-hydroxytetradecanoyl)-2-acetamido-2-deoxy-α-D-glucopyranose; Lipid X (derivative); 2-Acetamido-2-deoxy-α-D-glucopyranose 1-phosphate 3-(3-hydroxytetradecanoate); UDP-GlcNAc analogue precursor; GlcNAc-1-P-3-OH-C14; Monophosphoryl Lipid A precursor; (R)-GlcNAc-1-phosphate 3-hydroxymyristate
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Quality Control

Every batch of (R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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