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(R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) CAS NO 109304-40-7
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CAS No.:109304-40-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) is a sophisticated, multifunctional carbohydrate derivative that serves as a critical building block in advanced pharmaceutical and biochemical research. This compound's unique structure, featuring a phosphorylated sugar core esterified with a hydroxylated fatty acid chain, makes it invaluable for synthesizing complex glycoconjugates and lipid-linked intermediates. It is primarily sought after by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and biochemical probes.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of complex glycopeptide antibiotics and other bioactive molecules targeting bacterial cell walls.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphatases, and glycosyltransferases.
- Glycoconjugate Synthesis: Essential building block for creating novel vaccine adjuvants, drug delivery carriers, and diagnostic agents based on lipid A or related structures.
- Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in the search for new anti-infective and immunomodulatory agents.
- Process Development: Used in scaling up GMP-compliant manufacturing processes for advanced therapeutic candidates.
Basic Information
| Product Name | (R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) |
| CAS No. | 109304-40-7 |
| Molecular Formula | C22H42NO11P |
| Molecular Weight | 527.54 g/mol |
| Synonyms | 1-O-Phosphono-3-O-(3-hydroxytetradecanoyl)-2-acetamido-2-deoxy-α-D-glucopyranose; Lipid X (derivative); 2-Acetamido-2-deoxy-α-D-glucopyranose 1-phosphate 3-(3-hydroxytetradecanoate); UDP-GlcNAc analogue precursor; GlcNAc-1-P-3-OH-C14; Monophosphoryl Lipid A precursor; (R)-GlcNAc-1-phosphate 3-hydroxymyristate |
| EINECS | Contact for details |
Quality Control
Every batch of (R)-2-(Acetylamino)-2-Deoxy-α-D-Glucopyranose 1-(Dihydrogen Phosphate) 3-(3-Hydroxytetradecanoate) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment to support your regulatory and quality documentation.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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