Description

1-((Trifluoromethyl)Sulphonyl)-1H-Pyrrole is a specialized organosulfur compound featuring a reactive pyrrole ring substituted with a trifluoromethanesulfonyl (triflyl) group. This unique structure makes it a valuable high-performance building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for constructing complex molecules in drug discovery, particularly for candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the triflyl group enhances biological activity and stability.
• Material Science: Serves as a precursor for functional polymers and advanced electronic materials requiring specific sulfonyl and fluorinated motifs.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the trifluoromethanesulfonyl moiety into heterocyclic systems.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis in asymmetric synthesis.
• Life Sciences Research: Utilized as a biochemical probe or tool compound in mechanistic studies.

Basic Information

Product Name	1-((Trifluoromethyl)Sulphonyl)-1H-Pyrrole
CAS No.	109057-09-2
Molecular Formula	C5H4F3NO2S
Molecular Weight	199.15 g/mol
Synonyms	1H-Pyrrole, 1-[(trifluoromethyl)sulfonyl]-; 1-(Trifluoromethanesulfonyl)pyrrole; N-(Trifluoromethylsulfonyl)pyrrole; Pyrrole, 1-(trifluoromethylsulfonyl)-; Trifluoromethanesulfonyl pyrrole; N-Triflylpyrrole; TfN-Pyrrole; 1-Triflylpyrrole
EINECS	Contact for details

Quality Control

Our 1-((Trifluoromethyl)Sulphonyl)-1H-Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with stringent specifications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, providing full traceability and batch-to-batch consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.