Description

S(-)-Sch-23388 Des-Chloro- HCl is a high-purity, enantiomerically pure chemical compound used as a key reference standard and research tool in neuropharmacology. Its value lies in its specific activity as a potent and selective dopamine D1 receptor antagonist, making it critical for studying receptor function and signaling pathways. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on central nervous system (CNS) drug discovery and neurological research.

Application

• Neuroscience Research: Used as a selective pharmacological tool to study dopamine D1 receptor-mediated functions and behaviors in vitro and in vivo.
• Drug Discovery & Development: Serves as a critical reference standard and lead compound in the development of novel CNS-targeting therapeutics.
• Biochemical Assays: Employed in receptor binding studies, functional assays, and high-throughput screening (HTS) to characterize compound libraries.
• Academic Studies: Facilitates fundamental research into dopaminergic pathways, neuropsychiatric disorders, and molecular pharmacology.
• Metabolite & Impurity Standard: Acts as a certified reference material (CRM) for analytical method development and validation in pharmaceutical quality control.

Basic Information

Product Name	S(-)-Sch-23388 Des-Chloro- HCl
CAS No.	109010-52-8
Molecular Formula	C16H17ClN2O2 • HCl
Molecular Weight	349.23 g/mol
Synonyms	(S)-SCH-23388 Des-Chloro Hydrochloride; (S)-Des-Chloro SCH-23388 HCl; (S)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride; (S)-SKF-83566; (S)-Des-Chloro SKF-83566; (S)-Des-Chloro SCH-23390 Hydrochloride; (S)-7-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-8-ol Hydrochloride; (S)-D1 Dopamine Receptor Antagonist Des-Chloro Analog HCl
EINECS	Contact for details

Quality Control

Our S(-)-Sch-23388 Des-Chloro- HCl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.