Description

5-Hydroxy-2-oxo-2,3-dihydro-1H-[1]benzazephe-4-carboxylic acid ethyl ester is a high-purity, specialized benzazepine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a complex, functionalized scaffold essential for constructing novel pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development companies focused on creating new therapeutic agents, particularly in the areas of central nervous system and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Process Chemistry Development: Employed in route scouting and scale-up studies for complex organic molecule production.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	5-Hydroxy-2-oxo-2,3-dihydro-1H-[1]benzazephe-4-carboxylic acid ethyl ester
CAS No.	108993-98-2
Molecular Formula	C15H15NO4
Molecular Weight	273.28 g/mol
Synonyms	Ethyl 5-hydroxy-2-oxo-2,3-dihydro-1H-1-benzazepine-4-carboxylate; 1H-1-Benzazepine-4-carboxylic acid, 2,3-dihydro-5-hydroxy-2-oxo-, ethyl ester; 5-Hydroxy-2-oxo-2,3-dihydro-1H-1-benzazepine-4-carboxylic Acid Ethyl Ester; 108993-98-2; Ethyl 5-hydroxy-2-oxo-1,2,3,5-tetrahydro-4H-1-benzazepine-4-carboxylate; 4-Carbethoxy-5-hydroxy-2,3-dihydro-1H-1-benzazepin-2-one
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-oxo-2,3-dihydro-1H-[1]benzazephe-4-carboxylic acid ethyl ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.