Description

Glcnacβ(1-4)[Fucα(1-6)]Glcnac is a defined, high-purity oligosaccharide derivative, specifically a core fucosylated N,N'-diacetylchitobiose structure. This compound is a critical intermediate and reference standard in advanced glycoscience research and biopharmaceutical development. It is essential for scientists and manufacturers in the fields of glycobiology, enzymology, and therapeutic protein characterization who require precise tools for studying glycosylation patterns, enzyme specificity, and cell signaling pathways.

Application

• Glycobiology Research: Used as a key substrate or inhibitor for studying fucosyltransferase and glycosidase enzyme activities and mechanisms.
• Biopharmaceutical Development: Serves as a critical reference standard for the analysis and quality control of therapeutic glycoproteins, including monoclonal antibodies, where core fucosylation significantly impacts efficacy.
• Diagnostic Reagent Synthesis: Acts as a building block for synthesizing complex glycans used in diagnostic arrays and tools for detecting disease-specific antibodies or lectins.
• Enzyme Characterization: Employed in high-throughput screening assays to discover and characterize novel glycosyltransferases or glycosidases for industrial biocatalysis.
• Cell Signaling Studies: Utilized in research investigating lectin-carbohydrate interactions that mediate immune response, cell adhesion, and communication.
• Standards and Calibrants: Provides a well-defined molecular weight and structural standard for mass spectrometry (MS) and liquid chromatography (LC) analysis of complex carbohydrate mixtures.

Basic Information

Product Name	Glcnacβ(1-4)[Fucα(1-6)]Glcnac
CAS No.	108964-40-5
Molecular Formula	C22H38N2O16
Molecular Weight	586.54 g/mol
Synonyms	N,N'-Diacetylchitobiose, α1-6-fucosylated; Core Fucosylated Chitobiose; Fucα1-6GlcNAcβ1-4GlcNAc; [6-Fucosyl]-N,N'-diacetylchitobiose; 6-O-α-L-Fucopyranosyl-N,N'-diacetylchitobiose; Asn-linked glycan core structure; Glycan Core Pentasaccharide Fragment; 108964-40-5
EINECS	Contact for details

Quality Control

Every batch of Glcnacβ(1-4)[Fucα(1-6)]Glcnac is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing comprehensive analytical results, including purity by HPLC, structural confirmation by NMR and MS, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider storing desiccated at -20°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.