Description

(3R,6E,10S)-6,10α-Dimethyl-3-Isopropyl-6-Cyclodecene-1,4-Dione is a high-purity, chiral sesquiterpene derivative that serves as a critical advanced intermediate in organic synthesis. Its defined stereochemistry and unique bicyclic structure make it a valuable building block for the development of complex molecules with specific biological activities. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel fragrances, flavors, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in anti-inflammatory and anti-cancer drug discovery.
• Fragrance & Flavor Synthesis: Serves as a precursor for creating complex, high-value aroma chemicals with woody, amber, or musk-like olfactory profiles.
• Agrochemical Research: Used in the synthesis of novel bioactive compounds for crop protection and pest management solutions.
• Organic Synthesis & Catalysis: An important substrate for methodological studies in asymmetric synthesis, cycloaddition reactions, and catalyst development.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or structural properties.

Basic Information

Product Name	(3R,6E,10S)-6,10α-Dimethyl-3-Isopropyl-6-Cyclodecene-1,4-Dione
CAS No.	108944-67-8
Molecular Formula	C15H22O2
Molecular Weight	234.33 g/mol
Synonyms	6,10α-Dimethyl-3-(1-methylethyl)-6-cyclodecene-1,4-dione; (6E)-6,10α-Dimethyl-3-(propan-2-yl)cyclodec-6-ene-1,4-dione; (3R,6E,10S)-6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione; Chiral Sesquiterpene Dione; Isopropyl Dimethyl Cyclodecenedione; Advanced Sesquiterpenoid Intermediate
EINECS	Contact for details

Quality Control

Our (3R,6E,10S)-6,10α-Dimethyl-3-Isopropyl-6-Cyclodecene-1,4-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.