Description

6H-Furo[3,4-C]Pyrazol-6-One,3,3A,4,6A-Tetrahydro-4-Methoxy-,(3Ar,4R,6As)-Rel-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of proprietary drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up API production under GMP conditions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Asymmetric Synthesis: Utilized for introducing specific stereocenters in target molecules due to its defined (3aR,4R,6aS) relative configuration.

Basic Information

Item	Details
Product Name	6H-Furo[3,4-C]Pyrazol-6-One,3,3A,4,6A-Tetrahydro-4-Methoxy-,(3Ar,4R,6As)-Rel-(9Ci)
CAS No.	108943-26-6
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	(3aR,4R,6aS)-4-Methoxy-3a,4,6,6a-tetrahydro-1H-furo[3,4-c]pyrazol-6-one; rel-(3aR,4R,6aS)-Tetrahydro-4-methoxyfuro[3,4-c]pyrazol-6(1H)-one; 4-Methoxy-3a,4,6,6a-tetrahydro-1H-furo[3,4-c]pyrazol-6-one (rel-(3aR,4R,6aS)-form); Furo[3,4-c]pyrazol-6(1H)-one, 3a,4,6,6a-tetrahydro-4-methoxy-, (3aR,4R,6aS)-rel-; 108943-26-6; Advanced Chiral Furopyrazolone Intermediate.
EINECS	Contact for details

Quality Control

Our 6H-Furo[3,4-C]Pyrazol-6-One intermediate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided and can be tailored to support regulatory filings (e.g., FDA, EMA).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.