Description

(3R,4R)-3,4-Dihydroxycyclohexa-1,5-Diene-1-Carboxylic Acid is a high-purity chiral dihydroxy diene carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique stereochemistry and functional group array make it a valuable building block for constructing complex molecules with precise three-dimensional control. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those requiring specific stereocenters for biological activity.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts employed in enantioselective reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances where stereochemical purity is paramount.
• Academic & Process R&D: A valuable reagent for method development and exploring new synthetic routes in organic and medicinal chemistry research.
• Bioconjugate Chemistry: Potential use in creating labeled probes or linkers due to its carboxylic acid and diol functionalities.

Basic Information

Product Name	(3R,4R)-3,4-Dihydroxycyclohexa-1,5-Diene-1-Carboxylic Acid
CAS No.	108646-25-9
Molecular Formula	C7H8O4
Molecular Weight	156.14 g/mol
Synonyms	(3R,4R)-3,4-Dihydroxy-1,5-cyclohexadiene-1-carboxylic Acid; (3R-cis)-3,4-Dihydroxy-1,5-cyclohexadiene-1-carboxylic Acid; 1,5-Cyclohexadiene-1-carboxylic acid, 3,4-dihydroxy-, (3R,4R)-; Dihydrocaffeic Acid derivative; Chiral Dihydroxy Diene Carboxylic Acid
EINECS	Contact for details

Quality Control

Our (3R,4R)-3,4-Dihydroxycyclohexa-1,5-Diene-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, assay, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.