Description

12-Oxo-6,7,8,9,10,12-Hexahydro-Azepino[2,1-B]Quinazoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used extensively in research and development (R&D) for structure-activity relationship (SAR) studies and lead optimization processes.
• API Synthesis: A key starting material or intermediate in the production route of complex Active Pharmaceutical Ingredients (APIs) with quinazoline or azepine scaffolds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.
• Biochemical Tool Compound: May be used in vitro to study biological mechanisms and validate novel drug targets.

Basic Information

Product Name	12-Oxo-6,7,8,9,10,12-Hexahydro-Azepino[2,1-B]Quinazoline-3-Carboxylic Acid
CAS No.	108561-87-1
Molecular Formula	C14H14N2O3
Molecular Weight	258.27 g/mol
Synonyms	6,7,8,9,10,12-Hexahydroazepino[2,1-b]quinazoline-12-one-3-carboxylic acid; Azepino[2,1-b]quinazoline-3-carboxylic acid, 6,7,8,9,10,12-hexahydro-12-oxo-; 12-Oxo-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline-3-carboxylic acid; UNII-6Q2I0W8T0F; 6Q2I0W8T0F; SCHEMBL218021; CTK8C6681
EINECS	Contact for details

Quality Control

Our production of 12-Oxo-6,7,8,9,10,12-Hexahydro-Azepino[2,1-B]Quinazoline-3-Carboxylic Acid adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.