Description

n-Acetylglucosamine 6-Sulfate Sodium Salt is a key sulfated monosaccharide derivative, essential for research and development in glycosaminoglycan (GAG) biochemistry. Its primary value lies in its role as a critical building block and reference standard for studying heparin/heparan sulfate biosynthesis, structure, and biological activity. This high-purity biochemical is indispensable for pharmaceutical R&D, academic research, and the development of novel therapeutic agents targeting coagulation, inflammation, and cell signaling pathways.

Application

• Biochemical Research & Reference Standard: Serves as a crucial standard and substrate for enzymatic studies of sulfotransferases and sulfatases involved in GAG metabolism.
• Pharmaceutical Development: Used in the research and synthesis of heparin/heparan sulfate mimetics for anticoagulant, anti-inflammatory, and antiviral drug discovery.
• Enzyme Activity Assays: Acts as a specific substrate for assaying the activity of enzymes like GlcNAc 6-O-sulfotransferase.
• Glycobiology Studies: Fundamental for investigating carbohydrate-protein interactions, cell signaling, and extracellular matrix biology.
• Diagnostic Reagent Manufacturing: A key component in the production of diagnostic kits and reagents for metabolic disorder research.
• Cosmeceutical Research: Investigated for potential applications in skin health and wound healing due to its structural similarity to hyaluronic acid components.

Basic Information

Product Name	n-Acetylglucosamine 6-Sulfate Sodium Salt
CAS No.	108321-79-5
Molecular Formula	C8H14NNaO10S
Molecular Weight	339.25 g/mol
Synonyms	GlcNAc6S Sodium Salt; N-Acetyl-D-glucosamine 6-sulfate sodium salt; 2-Acetamido-2-deoxy-D-glucopyranose 6-(hydrogen sulfate) sodium salt; Sodium N-acetylglucosamine-6-sulfate; 6-O-Sulfo-N-acetylglucosamine sodium salt; D-Glucosamine, N-acetyl-6-O-sulfo-, sodium salt; NAG-6S Na; 2-(Acetylamino)-2-deoxy-D-glucose 6-sulfate sodium salt
EINECS	Contact for details

Quality Control

Our n-Acetylglucosamine 6-Sulfate Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles for production and can support regulatory filings. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a cool, dry place to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.