Description

5-Phospho-α-D-Ribosyl Diphosphate Sodium Salt is a crucial biochemical intermediate, serving as a key activated ribose donor in numerous biosynthetic pathways. Its primary commercial value lies in enabling research and production in nucleotide synthesis and metabolic studies. This high-purity compound is essential for pharmaceutical R&D, academic research, and the development of diagnostic reagents.

Application

• Pharmaceutical Research & Development: Critical substrate for enzymatic synthesis of nucleotides, nucleoside analogs, and other bioactive molecules.
• Biochemical Assay Kits: Used as a key component in assay kits for studying enzyme kinetics, particularly for phosphoribosyltransferases (PRTases).
• Metabolic Pathway Studies: Essential for in vitro research of de novo and salvage pathways for purine and pyrimidine biosynthesis.
• Academic & Industrial Enzymology: Serves as a standard reagent for characterizing and screening enzymes involved in nucleotide metabolism.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic tests for metabolic disorders.
• Precursor for Labeled Compounds: Acts as a starting material for the synthesis of isotopically labeled (e.g., 13C, 15N) nucleotides for advanced research.

Basic Information

Item	Details
Product Name	5-Phospho-α-D-Ribosyl Diphosphate Sodium Salt
CAS No.	108321-05-7
Molecular Formula	C5H8Na4O14P3 • xH2O
Molecular Weight	Anhydrous: 514.0 g/mol
Synonyms	PRPP Sodium Salt; Phosphoribosyl Pyrophosphate Sodium Salt; 5-Phosphoribosyl 1-Pyrophosphate Sodium Salt; α-D-5-Phosphoribosyl 1-Diphosphate Sodium Salt; Sodium PRPP; P-Rib-PP Na Salt; 5-O-Phosphono-α-D-ribofuranosyl Diphosphate Sodium Salt
EINECS	Contact for details

Quality Control

Our 5-Phospho-α-D-Ribosyl Diphosphate Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95% (Anhydrous Basis)
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.