Description

4-Bromo-2-Fluoro-5-Methoxyaniline Hcl is a high-purity, halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogen and methoxy functional groups.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials where its structural properties are advantageous.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex, color-fast dyes and organic pigments.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and other C-N or C-C bond-forming processes.
• Chemical Biology & Proteomics: Used as a reagent for modifying biomolecules or creating molecular probes for biological target identification.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Methoxyaniline Hcl
CAS No.	108310-38-9
Molecular Formula	C7H8BrFNO•HCl
Molecular Weight	266.51 g/mol (Free base: 220.05 g/mol)
Synonyms	1-Amino-4-bromo-2-fluoro-5-methoxybenzene hydrochloride; 5-Amino-2-bromo-4-fluoroanisole hydrochloride; 4-Bromo-2-fluoro-5-methoxybenzenamine hydrochloride; 2-Fluoro-4-bromo-5-methoxyaniline hydrochloride; Benzenamine, 4-bromo-2-fluoro-5-methoxy-, hydrochloride; 4-Bromo-2-fluoro-5-methoxyaniline monohydrochloride; Aniline, 4-bromo-2-fluoro-5-methoxy-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Methoxyaniline Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.