Description

1-Menthoxy-1-Butyne is a specialized alkyne ether derivative of menthol, offering a unique combination of a chiral terpene backbone with a reactive terminal alkyne functional group. This compound is valued for its role as a versatile chiral building block and intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with defined stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing the menthol-derived chiral center.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule impacts biological activity.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring a defined terpene character.
• Material Science Research: Employed in academic and industrial R&D for developing novel polymers or functional materials via click chemistry reactions utilizing the alkyne group.
• Catalyst and Ligand Development: Utilized as a starting material for synthesizing chiral ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Menthoxy-1-Butyne
CAS No.	108266-28-0
Molecular Formula	C₁₄H₂₄O
Molecular Weight	208.34 g/mol
Synonyms	1-Butyne, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy-; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl but-1-yn-1-yl ether; L-Menthoxy-1-Butyne; (-)-Menthoxy-1-Butyne; (1R)-Menthoxy-1-Butyne; 1-Butynyl Menthyl Ether; Menthyl 1-Butynyl Ether
EINECS	Contact for details

Quality Control

Our 1-Menthoxy-1-Butyne is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, identity confirmation by IR and NMR spectroscopy, and determination of chemical purity. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (GC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.