Description

3',4'-Difluoro-Biphenyl-4-Ol is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular structure, which is essential for constructing complex molecules with specific electronic and steric properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluoro-biphenyl core contributes to bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor or a core structure in the development of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the synthesis of organic semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorochemistry and medicinal chemistry.

Basic Information

Product Name	3',4'-Difluoro-Biphenyl-4-Ol
CAS No.	108185-80-4
Molecular Formula	C12H8F2O
Molecular Weight	206.19 g/mol
Synonyms	[1,1'-Biphenyl]-4-ol, 3',4'-difluoro-; 4-Hydroxy-3',4'-difluorobiphenyl; 3',4'-Difluoro-4-hydroxybiphenyl; 3',4'-Difluoro[1,1'-biphenyl]-4-ol; 4-(3,4-Difluorophenyl)phenol
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-Biphenyl-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.